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From: Sarah Vaughan on 21 Aug 2007 08:10
Anne Rogers wrote:
>
>> Thanks Anne. I vaguely remembered reading somewhere that I shouldn't
>> use it while breastfeeding so I refused it. Maybe it wasn't
>> recommended during pregnancy? I can't remember... Doesn't matter now
>> and I coped with the pain quite well with just the help of paracetemol
>> anyway. Good to know for the future, though, because I have a couple
>> of prolapsed disks and if my back goes crazy I now know that I can use
>> Voltaren rather than gritting my teeth and trying to cope on
>> paracetemol and heat packs alone.
>
> Not quite, NSAIDS are mostly considered ok in 1st and 2nd trimesters,
> but considered dangerous in the 3rd trimester, causing damage to the
> foetal kidney function and then other problems as a result of that.

I don't think they're considered OK in the 1st trimester either. I
remember reading a study that linked Ibuprofen consumption to increased
miscarriage risk, presumably due to the anti-prostaglandin effect.


All the best,

Sarah
--
http://www.goodenoughmummy.typepad.com

"That which can be destroyed by the truth, should be" - P. C. Hodgell

From: Anne Rogers on 21 Aug 2007 12:27

>> Not quite, NSAIDS are mostly considered ok in 1st and 2nd trimesters,
>> but considered dangerous in the 3rd trimester, causing damage to the
>> foetal kidney function and then other problems as a result of that.
>
> I don't think they're considered OK in the 1st trimester either. I
> remember reading a study that linked Ibuprofen consumption to increased
> miscarriage risk, presumably due to the anti-prostaglandin effect.

All the NSAIDS I looked up were given as B for 1st and 2nd and D for
3rd. Thus was from safefetus.net - it seemed to imply that for the
animal studies, the doses that caused defects, when translated to
equivalent human doses were toxic anyway. Obviously there's a difference
between giving a single dose and taking the medication regularly.

Cheers
Anne
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