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From: pautrey on 29 May 2010 10:24
IBD Linked to Antibiotic Use in Infancy
Wednesday May 26, 2010
A small study presented at Digestive Disease Week 2010 showed that
there may be a link between antibiotic use in infancy and the later
development of inflammatory bowel disease (IBD). Using data from
children in Manitoba, Canada, 36 children with IBD were compared with
360 children who did not have IBD. The researchers discovered that the
children with IBD were more likely to have had antibiotics in their
first year of life. The use of antibiotics in infancy increased the
risk of developing IBD by 3 times. Boys with IBD were 7 times more
likely to have had antibiotics, but there was no correlation found
between antibiotic use and girls with IBD.
Researchers hypothesize that the disruption in the bacteria in the gut
caused by antibiotics might be to blame for this increase in cases of
IBD. The gut flora is not well established until after the first year
of life, so use of antibiotics in infancy has a more profound effect
on the gastrointestinal tract than antibiotic use later in life.
This is a very small study, and larger studies would need to be done
in order to confirm the results. The authors also state that results
could be confounded because children who need antibiotics so early in
life might already be predisposed to developing IBD.
Shaw SY. "Antibiotic Prescriptions in the First Year of Life Increases
the Risk of Pediatric Inflammatory Bowel Disease: A Population-Based
Analysis (Abstract #95)." Digestive Disease Week 2010. 18 May 2010.