From: Mark Probert-Drew on 7 May 2010 22:03
On May 7, 9:37 pm, Jan Drew <jdrew63...(a)aol.com> wrote:
> Jan Drew wrote:
From: Mark Probert-Drew on 7 May 2010 22:06
On May 7, 9:45 pm, Jan Drew <jdrew63...(a)aol.com> wrote:
> Time to quit making a bigger fool of youself, Puta.
That is an incredible foul word in another language.
From: dr_jeff on 7 May 2010 22:23
Bob Officer wrote:
> And what type and the Amount of mercury they were exposed to and
> during exactly which part of fetal development matters.
> Donna is stuck in a fallacy loop.
From: Jan Drew on 7 May 2010 22:40
> Jan Drew wrote:
> > Jan Drew wrote:
> > Environ Health Perspect. 2009 Dec;117(12):1932-8. Epub 2009 Aug 19.
> > Mercury induces an unopposed inflammatory response in human peripheral
> > blood mononuclear cells in vitro.
> > Gardner RM, Nyland JF, Evans SL, Wang SB, Doyle KM, Crainiceanu CM,
> > Silbergeld EK.
> > Department of Environmental Health Sciences, Johns Hopkins Bloomberg
> > School of Public Health, Baltimore, Maryland 21205, USA.
> > Abstract
> > BACKGROUND: The human immune response to mercury is not well
> > characterized despite the body of evidence that suggests that Hg can
> > modulate immune responses, including the induction of autoimmune
> > disease in some mouse models. Dysregulation of cytokine signaling
> > appears to play an important role in the etiology of Hg-induced
> > autoimmunity in animal models. OBJECTIVES: In this study, we
> > systematically investigated the human immune response to Hg in vitro
> > in terms of cytokine release. METHODS: Human peripheral blood
> > mononuclear cells (PBMCs) were isolated from 20 volunteers who donated
> > blood six separate times. PBMCs were cultured with lipopolysaccharide
> > and concentrations of mercuric chloride (HgCl(2)) up to 200 nM. Seven
> > cytokines representing important pathways in physiologic and
> > pathologic immune responses were measured in supernatants. We used
> > multilevel models to account for the intrinsic clustering in the
> > cytokine data due to experimental design. RESULTS: We found a
> > consistent increase in the release of the proinflammatory cytokines
> > interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha, and
> > concurrent decrease in release of the antiinflammatory cytokines
> > interleukin 1-receptor antagonist (IL-1Ra) and IL-10 in human PBMCs
> > treated with subcytotoxic concentrations of HgCl(2). IL-4, IL-17, and
> > interferon-gamma increased in a concentration-response manner. These
> > results were replicated in a second, independently recruited
> > population of 20 different volunteers. CONCLUSIONS: Low concentrations
> > of HgCl(2) affect immune function in human cells by dysregulation of
> > cytokine signaling pathways, with the potential to influence diverse
> > health outcomes such as susceptibility to infectious disease or risk
> > of autoimmunity.
> > PMID: 20049214 [PubMed - indexed for MEDLINE
From: Jan Drew on 7 May 2010 22:42
On May 7, 9:45ï¿½pm, Jan Drew <jdrew63...(a)aol.com> wrote:
> ï¿½Time to quit making a bigger fool of youself, Puta.
Sorry, that is Putz.