From: pautrey on
On Jun 21, 12:08 am, Bob Officer <boboffic...(a)> wrote:
> On Sun, 20 Jun 2010 21:18:01 -0700 (PDT), in,
> pautrey <rpautr...(a)> wrote:
> >On Jun 20, 10:51 pm, Bob Officer <boboffic...(a)> wrote:
> >> On Sun, 20 Jun 2010 20:03:40 -0700 (PDT), in,
> >> Jan Drew <jdrew63...(a)> wrote:
> >> >On Jun 20, 10:54 pm, Bob Officer <boboffic...(a)> wrote:
> >> >> On Sun, 20 Jun 2010 22:48:22 -0400, in,
> >> >> dr_jeff <u...(a)> wrote:
> >> >> >Just what are we supposed to do with this little bit of information?
> >> >> autrey
> >> >Is not the subject.
> >> No one said he was Jan.
> >> But the question asked needed an answer. Do you have any idea what he
> >> was talking about. Neither do you.
> >> --
> >> Bob Officer
> >> Posting the truth
> >----------------------------------------------------------------
> >Sociopath,
> Is that your new title. I understand sociopaths do not believe in
> following rules of society. You seem to have some serious problems
> following rules.
> >I answered the fake MD.
> >Learn how to read.
> >Since you know so much, spend the next 24hrs
> >researching and writing a "concealed plagiarism nonsense
> >response", and post it like you, Peter B., and others normally do.
> You have no idea what the study was talking about of how to apply it
> in the real world.
> --
> Bob Officer
> Posting the truth Hide quoted text -
> - Show quoted text -


I'm rubber,
You're glue,
Everything you say,
Bounces off me,
& ...
From: trigonometry1972 on
On Jun 20, 7:48 pm, dr_jeff <u...(a)> wrote:
> Just what are we supposed to do with this little bit of information?

Well part of it would be the following:

J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):344-6.

Vitamin D as a defensin.

Adams JS.

Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai
Medical Center,
University of California, Los Angeles, CA 90048, USA. adamsj(a)

PMID: 17185816 [PubMed - indexed for MEDLINE]

The full article is available by way of link without charge.

That took one tiny search to find a relevant article.

And further down is an almost pure cry for a return to the land and
the farm with child labor in the barn ;-) And lots of
sun for mom and the kids without sunscreen or too
many clothes.

Make the jump and rub two brain cells together..............Trig
From: pautrey on
On Jun 21, 10:44 pm, "trigonometry1...(a) |"
<trigonometry1...(a)> wrote:


Innate Immune System Targets Asthma-Linked Fungus For Destruction

ScienceDaily (Sep. 5, 2008) — A new study shows that the innate immune
system of humans is capable of killing a fungus linked to airway
inflammation, chronic rhinosinusitis and bronchial asthma.

Researchers at Mayo Clinic and the Virginia Bioinformatics Institute
(VBI) have revealed that eosinophils, a particular type of white blood
cell, exert a strong immune response against the environmental fungus
Alternaria alternata. The groundbreaking findings shed light on some
of the early events involved in the recognition of A. alternata by the
human immune system.

Eosinophils typically combat parasitic invaders of the human body
larger than bacteria or viruses, such as flukes or parasitic worms
(collectively known as helminths). Evidence from different
experimental approaches suggests that asthma and chronic sinusitis can
arise when the body perceives that it has encountered a disease-
causing organism. Environmental fungi such as Alternaria do not
typically cause invasive infections like parasites but for some
reason, in certain people, the body responds as if it is being
attacked and chronic inflammation can result from the ensuing cascade
of immune-related events.

Read More:
From: trigonometry1972 on
On Jun 20, 7:48 pm, dr_jeff <u...(a)> wrote:
> Just what are we supposed to do with this little bit of information?

And I'll add vitamin D isn't the only player nutrient wise
relevant to immunity and innate immunity. Both vitamins
C and A have effects. The following abstract
indicates the vitamin A is relevant to immunity.
Certainly it is important in suboptimal diets low
in vitamin A found in Africa and Asia during hard times or on
south sea islands in the past.

1. J Immunol. 2008 Dec 1;181(11):7689-98.

Retinoic acids are potent inhibitors of
spontaneous human eosinophil apoptosis.

Ueki S, Mahemuti G, Oyamada H, Kato H,
Kihara J, Tanabe M, Ito W, Chiba T, Takeda
M, Kayaba H, Chihara J.

Department of Clinical and Laboratory Medicine,
Akita University School of
Medicine, Akita, Japan.

Retinoic acids (RAs), which are active metabolites
of vitamin A, are known to enhance Th2-type immune
responses in vitro, but the role of RAs in allergic
inflammatory cells remains unclear. In this study,
we demonstrated that purified peripheral blood
eosinophils expressed nuclear receptors for RAs
at the mRNA and protein levels. Eosinophils cultured
with all-trans RA (ATRA) and 9-cis-RA showed
dramatically induced cell survival and nuclear
hypersegmentation, and the efficacy of RAs (10(-6)M)
was similar to that of IL-5 (1 ng/ml), the most
critical cytokine for eosinophil activation.
Pharmacological manipulation with
receptor-specific agonists and antagonists indicated
that the antiapoptotic effect of RAs was mediated
through ligand-dependent activation of both retinoid
acid receptors and retinoid X receptors (mainly retinoid
acid receptors). Furthermore, using a gene microarray
and a cytokine Ab array, we discovered that
RAs induced vascular endothelial growth factor,
M-CSF, and MCP-1 secretion, although they were not
involved in eosinophil survival. RA-induced eosinophil
survival appears to be associated with down-regulation
of caspase 3 and inhibition of its enzymatic activity.
These findings indicate an important role
of RAs in homeostasis of granulocytes
and provide further insight into the
cellular and molecular pathogenesis of
allergic reactions.

PMID: 19017957 [PubMed - indexed for MEDLINE]

From: trigonometry1972 on
On Jun 21, 8:56 pm, pautrey <rpautr...(a)> wrote:
> On Jun 21, 10:44 pm, "trigonometry1...(a) |"
> >
> Read More:

I got that. Is this a comment?